HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 59655142, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | HCID 11367715 | HCID 11367715 | — |
| Reactant | HCID 69312550 | HCID 69312550 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 59655142 | HCID 59655142 | — |
Reaction Steps
Prepared by saponification of ethyl rac.-2-(1-tert-butoxycarbonyl-1H-5-chloroindol-2-yl)pent-4-enoate to rac.-2-(5-chloro-1H-indol-2-yl)pent-4-enoic acid analogously to Example 1f and subsequent amide coupling analogously to Example 1g with 3-methyl-4-(pyrrolidin-1-ylcarbonyl)aniline, TBTU, diisopropylethylamine in tetrahydrofuran. C25H26ClN3O2 (435.96); mass spectrum: (M+H)+=435.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-312f86f876664ab0882ef5d2d630f18f |
| Source note | uspto-grants-2008_02 |