Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69199271, compound

HRID 2054102Notes

Reaction equation

HRID 2054102 reaction equation
[CH3:1][C:2]1[NH:6][N:5]=[C:4]([NH:7][C:8]2[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][CH:9]=2)[CH:3]=1.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:29].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:29].[ClH:29].[CH3:1][C:2]1[NH:6][N:5]=[C:4]([NH:7][C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)[CH:3]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 23104489HCID 23104489, compound

Product 1

HCID 69199271HCID 69199271, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 5-methyl-N-(4-nitrophenyl)-1H-pyrazol-3-amine (1) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-2ae2cf9c14b047d6b19e28a560d68923
Source dataset
uspto-grants-2008_02
Patent number
US07329288B2

Reaction notes

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