Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69201302, compound

HRID 2054104Notes

Reaction equation

HRID 2054104 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11]2[C:16]([OH:17])=[CH:15][CH:14]=[CH:13][N:12]=2)=[CH:6][CH:5]=1)([O-])=O.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:30].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:30].[ClH:30].[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:10][C:11]2[C:16]([OH:17])=[CH:15][CH:14]=[CH:13][N:12]=2)=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 23104487HCID 23104487, compound

Product 1

HCID 69201302HCID 69201302, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 2-[(4-nitrophenyl)amino]pyrid-3-ol (3) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-49ed5446e21248009051ebe86645d69c
Source dataset
uspto-grants-2008_02
Patent number
US07329288B2

Reaction notes

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