Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69199445, compound

HRID 2054110Notes

Reaction equation

HRID 2054110 reaction equation
[CH3:1][C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([N+:15]([O-])=O)=[CH:11][CH:10]=2)[CH:5]=[CH:4][CH:3]=1.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:30].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:30].[ClH:30].[CH3:1][C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:10]=[CH:11][C:12]([NH2:15])=[CH:13][CH:14]=2)[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 23104478HCID 23104478, compound

Product 1

HCID 69199445HCID 69199445, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 6-methyl-N-(4-nitrophenyl)pyrid-2-amine (9) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-e96d0c8cfe5b4c3094cc54b9183543ad
Source dataset
uspto-grants-2008_02
Patent number
US07329288B2

Reaction notes

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