Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69203437, compound

HRID 2054114Notes

Reaction equation

HRID 2054114 reaction equation
[CH3:1][C:2]1[CH:11]=[C:10]([NH:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:34].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:34].[ClH:34].[CH3:1][C:2]1[CH:11]=[C:10]([NH:12][C:13]2[CH:18]=[CH:17][C:16]([NH2:19])=[CH:15][CH:14]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 3137242HCID 3137242, compound

Product 1

HCID 69203437HCID 69203437, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 2-methyl-N-(4-nitrophenyl)quinol-4-amine (13) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-046358a8bf3f4bd191ec1cf64d706537
Source dataset
uspto-grants-2008_02
Patent number
US07329288B2

Reaction notes

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