HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1H-imidazole-4-carbonitrile → HCID 67213274, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1H-imidazole-4-carbonitrile | HCID 78777 | — |
| Reactant | 4,4,4-Trifluoro-1-(m-tolyl)butane-1,3-dione | HCID 18624099 | — |
| Product | HCID 67213274 | HCID 67213274 | 53.3% |
Reaction Steps
Reaction of 1-(3-methyl-phenyl)-4,4,4-trifluoro-butane-1,3-dione (230 mg, 1.0 mmol), prepared from commercially available 3-methyl-acetophenone according to general procedure A, and 4-amino-5-cyano-1H-imidazole (108 mg, 1.0 mmol) according to general procedure B yielded the title compound as a yellow solid (161 mg, 53%). MS (ISP) 302.9 [(M+H)+]; mp 202° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329662B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-4ce5a2941e8c407a84217775fdf1231f |
| Source note | uspto-grants-2008_02 |