HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-dihydro-2H-pyran → HCID 59655786, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| Reactant | HCID 21575569 | HCID 21575569 | — |
| Reactant | HCID 59655782 | HCID 59655782 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 59655786 | HCID 59655786 | 65% |
Reaction Steps
Following the same procedure as for 2-[2-Phthalimido-1-(2,3,5,6-tetrahydropyran-2-yl)oxyethyl]-7-azaindole . From 8b (3.8 g, 11 mmol) in CHCl3 (350 ml), 6N HCl in benzene (35 ml) and 2,3-dihydropyrane (10 ml, 110 mmol). 4Methoxy-2-[2-phthalimido-1-(2,3,5,6-tetrahydropyran-2-yl)oxyethyl]-7-azaindole (3.07 g, 65%) as a diastereomeric mixture (1:1) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329666B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-96702236a733485bbd20f91d98d5a6bf |
| Source note | uspto-grants-2008_02 |