Dichloromethane → HCID 10268157, compound

Participants

Reaction Steps

To a cooled (0° C.) solution of 21 (20 mg, 0.07 mmol) in CH2Cl2 (5 ml) mCPBA (32 mg, 0.13 mmol) was added. The mixture was stirred for 30 min. A saturated aq. Na2S203 solution was added (1 ml) and was basified with saturated aq. Na2CO3. The organic layer was separated and the aqueous layer extracted with CH2Cl2. The organic solutions were dried and evaporated together to give 9-amino-5-(2-methanesulfinylpyrimidin-4-yl)pyrido[3′,2′:4,5]-pyrrolo[1,2-c]pyrimidine (20 mg, 90%).

Provenance & Evidence