Dichloromethane → HCID 9924030, compound

Participants

Reaction Steps

To solution of 21 (200 mg, 0.65 mmol) in CH2Cl2 (50 ml) mCPBA (320 mg, 1.30 mmol) was added. The mixture was stirred for 2 hours at room temperature. A saturated aq. Na2S2O3 solution was added (5 ml) and was basified with saturated aq. Na2CO3. The organic layer was separated and the aqueous layer extracted with CH2Cl2. The organic solutions were dried and evaporated together to give 9-Amino-5-(2-methanesulfonylpyrimidin-4-yl)pyrido[3′,2′:4,5]-pyrrolo[1,2-c]pyrimidine(201 mg, 91%).

Provenance & Evidence