HCID 22663345, compound → Benzoic acid, 2,3-diamino-4-methoxy-, methyl ester (9CI)

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Reaction Steps

A solution of methyl 2-amino-4-methoxy-3-nitrobenzoate (1.84 g, Reference Example 9) in ethanol (100 ml) was treated with 10% palladium on carbon (0.2 g). The resulting suspension was stirred under 3 atmospheres of hydrogen for 3 hours. The catalyst was then removed by filtration and the filtrate evaporated to give the title compound (1.6 g) as a black solid which was used without further purification. M+196.

Provenance & Evidence