反应详情

温度

0 °C

Cyclodecanone (n=6) (1.0 g) in 10 mL concentrated sulfuric acid was cooled to 0° C. and 0.54 g of sodium azide was added. The reaction continued to stir at 0° C. for 1 h and warmed to room temperature where it was stirred for two h. The solution was diluted with cold water and treated with cold 10% NaOH solution until pH=9. Extraction with ether (2×), drying over magnesium sulfate and evaporation of solvent provided 1.23 g of 2-azacycloundecanone.

1. temperaturewarmed to room temperature where it
2. stirringwas stirred for two h
3. extractionExtraction with ether (2×)
4. dry with materialdrying over magnesium sulfate and evaporation of solvent