Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Methoxyaniline | HCID 10824 | — |
| Reactant | 3-Fluoro-4-nitrophenol | HCID 520948 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21938003 | HCID 21938003 | — |
Reaction Steps
4 g of 3-fluoro-4-nitrophenol and 9.4 g of m-anisidine were mixed and stirred for 2.5 hours at 150° C. After cooling, it was dissolved in dichloromethane and extracted three times with 1N aqueous hydrochloric acid. The organic phase was dried on sodium sulfate, concentrated by evaporation in a vacuum, and the residue was chromatographed on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07329679B2 |
|---|
| Source dataset | uspto-grants-2008_02 |
|---|
| ORD ID | ord-1f0ba0e463994bf5a8bd1fb326f3d037 |
|---|
| Source note | uspto-grants-2008_02 |
|---|
