HRID2054649

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66279

1-Propanesulfonyl chloride

C3H7ClO2S

结构：CC(C)OC(=O)CCCCCOc1cc2c(cc1N)nc(-c1ccccc1)n2-c1ccccc1

HCID67364042

未命名化合物

PRODUCTS

生成物

结构：CCCS(=O)(=O)Nc1cc2nc(-c3ccccc3)n(-c3ccccc3)c2cc1OCCCCCC(=O)OC(C)C

HCID11997938

6-[[1,2-Diphenyl-5-[(propylsulfonyl)amino]-1H-benzimidazol-6-yl]oxy]hexanoic acid isopropyl ester

C31H37N3O5S

PROCEDURE

实验过程

6-[(5-Amino-1,2-diphenyl-1H-benzimidazol-6-yl)oxy]hexanoic acid isopropyl ester was reacted according to general operating instructions 13 with propanesulfonic acid chloride.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-197516d62a59443481d6957515c4cd84
来源数据集: uspto-grants-2008_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07329679B2
来源说明: uspto-grants-2008_02

反应 SMILES

[CH:1]([O:4][C:5](=[O:34])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[C:13]([NH2:33])=[CH:14][C:15]2[N:19]=[C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[N:17]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[C:16]=2[CH:32]=1)([CH3:3])[CH3:2].[CH2:35]([S:38](Cl)(=[O:40])=[O:39])[CH2:36][CH3:37]>>[CH:1]([O:4][C:5](=[O:34])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[C:13]([NH:33][S:38]([CH2:35][CH2:36][CH3:37])(=[O:40])=[O:39])=[CH:14][C:15]2[N:19]=[C:18]([C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)[N:17]([C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)[C:16]=2[CH:32]=1)([CH3:3])[CH3:2]