HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 21938149, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | HCID 21937968 | HCID 21937968 | — |
| Catalyst | Cupric acetate | HCID 8895 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 21938149 | HCID 21938149 | — |
Reaction Steps
2.5 g of 4-bromo-6-methoxy-2-phenyl-1H-benzimidazole and 2.24 g of 4-(methylbenzene)boronic acid were stirred with 1.5 g of anhydrous copper(II) acetate and about 3 g of molecular sieve in 35 ml of pyridine for 7 hours at 100° C. After dichloromethane and Celite were added, it was concentrated by evaporation and chromatographed on silica gel with a hexane/ethyl acetate mixture.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329679B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-5b678a07155b49faaeefdad4ccbbf251 |
| Source note | uspto-grants-2008_02 |