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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2054679Generated: October 27, 2026

4-(Trifluoromethyl)benzenesulfonyl chloride → 6-[[5-[[(4-(Trifluoromethyl)phenyl)sulfonyl]amino]-1-(4-methoxyphenyl)-2-phenyl-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl ester

https://huagongshe.com/reaction/2054679

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzenesulfonyl chlorideHCID 2777399—
Reactant6-[(5-Amino-1-(4-methoxyphenyl)-2-phenyl-1H-benzimidazol-6-yl)oxy]hexanoic acid methyl esterHCID 67364071—
Product6-[[5-[[(4-(Trifluoromethyl)phenyl)sulfonyl]amino]-1-(4-methoxyphenyl)-2-phenyl-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl esterHCID 10211853—

Reaction Steps

6-[(5-Amino-1-(4-methoxyphenyl)-2-phenyl-1H-benzimidazol-6-yl)oxy]hexanoic acid methyl ester was reacted with 4-(trifluoromethyl)benzenesulfonic acid chloride according to general operating instructions 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07329679B2
Source datasetuspto-grants-2008_02
ORD IDord-4742d25aa3e74f3eb3e60aea3e11578f
Source noteuspto-grants-2008_02