Quinaldic Acid → HCID 9947131, compound
Reaction equation
[C:1]([OH:13])(=O)[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[F:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH2:22][N:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)=[CH:17][CH:16]=1>>[F:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH2:22][N:23]2[CH2:24][CH2:25][N:26]([C:1]([C:2]3[CH:11]=[CH:10][C:9]4[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=4)[N:3]=3)=[O:13])[CH2:27][CH2:28]2)=[CH:17][CH:16]=1Participants
3
Procedure
Analogously to Example 1, quinaldic acid is reacted with 1-[2-(4-fluoro-phenyl)ethyl]piperazine, giving {4-[2-(4-fluorophenyl)ethyl]piperazin-1-yl}-quinolin-2-ylmethanone.
Sources & evidence
- ORD record
- ord-3590057df4754d0d8d4312615577caf1
- Source dataset
- uspto-grants-2008_02
- Patent number
- US07329749B2
Reaction notes
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