Pyridine → HCID 59656663, compound

Participants

Reaction Steps

To a stirred mixture of the above amide (0.2 g, 0.8 mmol) and pyridine (2.0 mL) in THF at 0° C. was added methanesulfonyl chloride (0.46 g, 4.0 mmol). The reaction was stirred at room temperature overnight. It was next diluted with water and extracted with dichloromethane (20 mL). The solvent was removed and purified by preparative TLC (5% EtOAc in CH2Cl2) to afford the title compound (20 mg, 7.6%).

Provenance & Evidence