huagongshe.com
HRID2054924

反应详情

EQUATION

反应方程式

HRID 2054924 的结构方程式

REACTANTS

反应物

2
结构：Nc1nccc2ccccc12
HCID73742

1-Aminoisoquinoline

C9H8N2

结构：COc1ccc(F)cc1C(C)(C)CC1(C(F)(F)F)CO1
HCID16099239

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(F)cc1C(C)(C)CC(O)(CNc1nccc2ccccc12)C(F)(F)F
HCID21948812

未命名化合物

收率 21.9%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCC.CCOC(C)=O
溶剂HCID21226206

未命名化合物

PROCEDURE

实验过程

Analogously to Example 1, 200 mg (0.68 mmol) of 2-[2-(5-fluoro-2-methoxyphenyl)-2-methylpropyl]-2-(trifluoromethyl)oxirane and 99 mg (0.68 mmol) of 1-aminoisoquinoline are reacted. After chromatography on silica gel with hexane-ethyl acetate (0-60%), 65 mg of product is obtained.