HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Quinolinamine, 2-methyl- → HCID 21948887, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Quinolinamine, 2-methyl- | HCID 148683 | — |
| Reactant | HCID 21948855 | HCID 21948855 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | HCID 21948887 | HCID 21948887 | 58.8% |
Reaction Steps
Analogously to Example 1, 500 mg (2.05 mmol) of 2-(2-methyl-2-phenylpropyl)-2-(trifluoromethyl)oxirane and 650 mg (4.10 mmol) of 5-amino-2-methylquinoline are reacted. After chromatography on silica gel with hexane-ethyl acetate (0-70%), 485 mg of product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329753B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-cad58cb90c6546a887cf7f33cd8a0955 |
| Source note | uspto-grants-2008_02 |