HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2-Ethoxy-5-nitroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | o-Toluenesulfonyl chloride | HCID 8623 | — |
| Reactant | 5-Nitroquinoline 1-oxide | HCID 82085 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Ethoxy-5-nitroquinoline | HCID 21948830 | — |
Reaction Steps
A suspension of 1 g (5 mmol) of 5-nitroquinoline-1-oxide, 1.23 g (6.4 mmol) of toluenesulfonic acid chloride and 1.4 ml (9.9 mmol) of triethylamine in 30 ml of EtOH is stirred for 60 hours at room temperature. The solid is suctioned off and washed with EtOH: 870 mg of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329753B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-feda0fe87f1e4195b0032e37033907cb |
| Source note | uspto-grants-2008_02 |