HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethoxy-5-nitroquinoline → 2-Ethoxyquinolin-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethoxy-5-nitroquinoline | HCID 21948830 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Ethoxyquinolin-5-amine | HCID 21948876 | — |
Reaction Steps
860 mg (3.9 mmol) of 2-ethoxy-5-nitroquinoline is stirred in 25 ml of ethyl acetate in the presence of 235 mg of 10% Pd—C for 4.5 hours in a hydrogen atmosphere. The batch is filtered, and the filtrate is concentrated by evaporation: 720 mg of a light yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329753B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-2f7cc5e61f4446b2bbe7c7ec96d6791d |
| Source note | uspto-grants-2008_02 |