HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 21948929, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 5-Nitro-2-quinolinemethanol | HCID 4913360 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 21948929 | HCID 21948929 | — |
Reaction Steps
A solution that consists of 390 mg (1.91 mmol) of 2-(hydroxymethyl)-5-nitroquinoline and 2.5 ml of acetic acid anhydride in 5.0 ml of pyridine is allowed to stir for 24 hours at room temperature. After repeated co-evaporation with toluene and subsequent chromatography on silica gel with hexane-ethyl acetate (0-100%), 410 mg (87% of theory) of the product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329753B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-55c73acd04dc473fade0a1acfbd6e181 |
| Source note | uspto-grants-2008_02 |