反应详情

Analogously to Example 40, 340 mg (0.69 mmol) of 5-[4-(4-chloro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentylidenamino]quinoline-2-carboxylic acid amide is dissolved in 10 ml of methanol and mixed several times with 110 mg (2.89 mmol) of sodium borohydride. After working-up and purification on silica gel with hexane-ethyl acetate (0-100%), 280 mg (82% of theory) of the product is obtained.

1. custompurification on silica gel with hexane-ethyl acetate (0-100%), 280 mg (82% of theory) of the product
2. customis obtained