HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-Nitro-1,2-dihydroisoquinolin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 5-nitro-1H-isochromen-1-one | HCID 10012760 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Nitro-1,2-dihydroisoquinolin-1-one | HCID 231378 | 79.7% |
Reaction Steps
2.51 g (13.13 mmol) of 5-nitroisocoumarin is added to 100 ml of ethanol. Ammonia is pressure-forced in in an autoclave. The product precipitates and is suctioned off. 1.98 g (79.7%) of the desired compound is isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329753B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-e949f766b90a4453ad954f3bbab75f01 |
| Source note | uspto-grants-2008_02 |