HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Nitrobenzo[d][1,3]dioxole-4-carboxylic acid → 7-Amino-1,3-dioxaindane-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Nitrobenzo[d][1,3]dioxole-4-carboxylic acid | HCID 21948804 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 7-Amino-1,3-dioxaindane-4-carboxylic acid | HCID 21948822 | 98.7% |
Reaction Steps
8.05 g of 7-nitro-benzo[1,3]dioxole-4-carboxylic acid is reacted with hydrogen in 650 ml of ethanol with 800 mg of palladium/carbon catalyst under normal pressure at room temperature. It is filtered through diatomaceous earth and concentrated by evaporation in a vacuum. 6.82 g of 7-amino-benzo[1,3]dioxole-4-carboxylic acid is obtained as a brown solid, flash point 196-197° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329753B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-1c81d56428284659b175840058fee591 |
| Source note | uspto-grants-2008_02 |