1-(2-{4-[2,8-Bis-(tert-butyl-dimethyl-silyloxy)-5,11-dihydro-chromeno[4,3-c]-chromen-5-yl]-phenoxy}-ethyl)-piperidine → HCID 11515717, compound

HRID 2055035Notes

Reaction equation

C([Si](C)(C)[O:6][C:7]1[CH:8]=[CH:9][C:10]2[C:11]3[CH:24]([C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)[O:23][C:22]4[CH:21]=[C:20]([O:31][Si](C(C)(C)C)(C)C)[CH:19]=[CH:18][C:17]=4[C:12]=3[CH2:13][O:14][C:15]=2[CH:16]=1)(C)(C)C.C([Si](C)(C)OC1C=CC2C3C(C4C=CC(OCCN5CCCCC5)=CC=4)OC4C=C(O[Si](C(C)(C)C)(C)C)C=CC=4C=3COC=2C=1)(C)(C)C>>[C:25]1([CH:24]2[C:11]3[C:10]4[CH:9]=[CH:8][C:7]([OH:6])=[CH:16][C:15]=4[O:14][CH2:13][C:12]=3[C:17]3[CH:18]=[CH:19][C:20]([OH:31])=[CH:21][C:22]=3[O:23]2)[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

Participants

Reactant 2

HCID 115566601-(2-{4-[2,8-Bis-(tert-butyl-dimethyl-silyloxy)-5,11-dihydro-chromeno[4,3-c]-chromen-5-yl]-phenoxy}-ethyl)-piperidine

HCID 11685609HCID 11685609, compound

Product 1

HCID 11515717HCID 11515717, compound

Procedure

The title product was prepared according to the procedure described in Example 44 with substitution of 2,8-Bis-(tert-butyl-dimethyl-silyloxy)-5-phenyl-5,11-dihydro-chromeno[4,3-c]-chromene, prepared as in Example 41, for 1-(2-{4-[2,8-Bis-(tert-butyl-dimethyl-silyloxy)-5,11-dihydro-chromeno[4,3-c]-chromen-5-yl]-phenoxy}-ethyl)-piperidine.

Sources & evidence

ORD record: ord-daf339e38a4f4088a234ebe18558d8ac
Source dataset: uspto-grants-2008_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07329654B2

Reaction notes

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