HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosuccinimide → 2-Amino-5-Chloro-alpha-(Methoxyimino)-4-Thiazoleacetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | 2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid | HCID 125216 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Amino-5-Chloro-alpha-(Methoxyimino)-4-Thiazoleacetic Acid | HCID 54009366 | — |
Reaction Steps
To 500 mL of DMF were added 50.0 g (250 mmol) of 2-amino-α-(methoxyimino)-4-thiazoleacetic acid and 35 g (260 mmol) of N-chlorosuccinimide. The mixture was stirred at room temperature overnight, after which time mass spectral analysis showed no more starting material to be present. The light brown solution was used without further manipulation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07332471B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-788b01ce8d5e46d0a0d77eb7e47ac345 |
| Source note | uspto-grants-2008_02 |