HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine, 4-(chloroacetyl)- → HCID 59657712, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine, 4-(chloroacetyl)- | HCID 74040 | — |
| Reactant | 1'-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 59657599 | — |
| Product | HCID 59657712 | HCID 59657712 | — |
Reaction Steps
Following the general procedure V as described hereinabove, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (the preparation of which has been described in example 16) with commercially available 2-chloro-1-morpholin-4-yl-ethanone as electrophile, the title compound was obtained as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07332501B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-54679f0fad04405997904264af1bb104 |
| Source note | uspto-grants-2008_02 |