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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2055447Generated: October 30, 2026

1-Piperidinecarbonyl chloride → HCID 59657549, compound

https://huagongshe.com/reaction/2055447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Piperidinecarbonyl chlorideHCID 242085—
Reactant1'-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 59657599—
ProductHCID 59657549HCID 59657549—

Reaction Steps

Following the general procedure V as described hereinabove, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (the preparation of which has been described in example 16) with commercially available piperidine-1-carbonyl chloride as electrophile, the title compound was obtained as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07332501B2
Source datasetuspto-grants-2008_02
ORD IDord-4404034b21bd4bdf99e3408fa03b2a59
Source noteuspto-grants-2008_02