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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2055456Generated: October 25, 2026

1-(4-ethoxyphenyl)-5-methoxy-2-methyl-1H-indole-3-carboxylic acid → HCID 57978137, compound

https://huagongshe.com/reaction/2055456

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-ethoxyphenyl)-5-methoxy-2-methyl-1H-indole-3-carboxylic acidHCID 742160—
Reactant3H-spiro(isobenzofuran-1,4'-piperidin)-3-oneHCID 9834255—
ProductHCID 57978137HCID 57978137—

Reaction Steps

Following the general procedure I as described above, the acylation of 3H-spiro[2-benzofuran-1,4′-piperidin]-3-one prepared as described in example 16, with commercially available 1-(4-ethoxyphenyl)-5-methoxy-2-methyl-1H-indole-3-carboxylic acid, gave the title compound. ES-MS m/e (%): 511.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07332501B2
Source datasetuspto-grants-2008_02
ORD IDord-364e5adf91544d4aa855e8187513f9b9
Source noteuspto-grants-2008_02