HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)-2-methylpyridine → HCID 59657548, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)-2-methylpyridine | HCID 12675262 | — |
| Reactant | 1'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 59657623 | — |
| Product | HCID 59657548 | HCID 59657548 | — |
Reaction Steps
Following the general procedure III as described above, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (prepared according to example 19) with 4-chloromethyl-2-methyl-pyridine (described in WO 2006023707) gave the title compound. ES-MS m/e (%): 504.2(M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07332501B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-2c53c6a2c4e440cfa7aa93ffd528b9b0 |
| Source note | uspto-grants-2008_02 |