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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2055488Generated: October 31, 2026

4-(Bromomethyl)pyridine → HCID 59657693, compound

https://huagongshe.com/reaction/2055488

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Bromomethyl)pyridineHCID 642799—
Reactant1'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 59657623—
ProductHCID 59657693HCID 59657693—

Reaction Steps

Following the general procedure III as described above, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (prepared according to example 19) with commercially available 4-bromomethyl-pyridine gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07332501B2
Source datasetuspto-grants-2008_02
ORD IDord-3c3178c127da4ac08a37bd928ceaec4f
Source noteuspto-grants-2008_02