HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Ethyl 5-cyclopropyl-2-methyl-1,3-oxazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 69016854 | HCID 69016854 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Ethyl 5-cyclopropyl-2-methyl-1,3-oxazole-4-carboxylate | HCID 59657553 | 34% |
Reaction Steps
2-Acetylamino-2-cyclopropanecarbonyl-malonic acid diethyl ester in DMSO was treated with 2 eq H2O and stirred at room temperature for 6 h then extracted with Et2O to give after concentration the title compound in 34% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07332501B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-d5a7a025ae434c0280bd66da21af7b16 |
| Source note | uspto-grants-2008_02 |