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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2055525Generated: November 2, 2026

(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone → HCID 59657686, compound

https://huagongshe.com/reaction/2055525

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanoneHCID 15951937—
ReactantMethanesulfonic acid pyridin-2-ylmethyl esterHCID 22417657—
ProductHCID 59657686HCID 59657686—

Reaction Steps

Following the general procedure III as described above, the alkylation of 1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidine] (prepared according to example 69) with methanesulfonic acid pyridin-2-ylmethyl ester (described in WO 9955318) gave the title compound. ES-MS m/e (%): 458.3(M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07332501B2
Source datasetuspto-grants-2008_02
ORD IDord-6cac4ffaae7549958da8a2bec44ad584
Source noteuspto-grants-2008_02