2,4-Difluorophenylboronic acid → HCID 86595312, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.[F:16][C:17]1[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:18]=1B(O)O>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:20]3[CH:19]=[CH:18][C:17]([F:16])=[CH:22][C:21]=3[F:23])[CH:14]=2)[CH:5]=[CH:4][N:3]=1Participants
3
Procedure
The title compound, MS: m/e=330.4 (M+H+), was prepared in accordance with the general method of example 7 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2,4-difluorobenzene boronic acid.
Sources & evidence
- ORD record
- ord-4f0607eb8a6d4e329d4c666fb5e72fdb
- Source dataset
- uspto-grants-2008_02
- Patent number
- US07332510B2
Reaction notes
Loading…