4-Cyanobenzoyl chloride → HCID 68805840, compound
Reaction equation
[CH:1]1([N:6]2[CH2:11][CH2:10][CH:9]([CH2:12][CH2:13][C:14]([NH:16][OH:17])=[NH:15])[CH2:8][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:18]([C:20]1[CH:28]=[CH:27][C:23]([C:24]([Cl:26])=O)=[CH:22][CH:21]=1)#[N:19]>>[ClH:26].[CH:1]1([N:6]2[CH2:7][CH2:8][CH:9]([CH2:12][CH2:13][C:14]3[N:15]=[C:24]([C:23]4[CH:27]=[CH:28][C:20]([C:18]#[N:19])=[CH:21][CH:22]=4)[O:17][N:16]=3)[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
3
Procedure
The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-(1-cyclopentylpiperidin-4-yl)-N-hydroxypropionamidine and 4-cyanobenzoyl chloride.
Sources & evidence
- ORD record
- ord-ac93cce665a54818be9f67539cbc0635
- Source dataset
- uspto-grants-2008_02
- Patent number
- US07332508B2
Reaction notes
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