2-Fluoro-4-(trifluoromethyl)benzoyl chloride → HCID 68805823, compound

HRID 2055681Notes

Reaction equation

HRID 2055681 reaction equation
[CH2:1]([CH:3]([N:6]1[CH2:11][CH2:10][CH:9]([CH2:12][C:13]([NH:15][OH:16])=[NH:14])[CH2:8][CH2:7]1)[CH2:4][CH3:5])[CH3:2].[F:17][C:18]1[CH:26]=[C:25]([C:27]([F:30])([F:29])[F:28])[CH:24]=[CH:23][C:19]=1[C:20]([Cl:22])=O>>[ClH:22].[CH2:1]([CH:3]([N:6]1[CH2:11][CH2:10][CH:9]([CH2:12][C:13]2[N:14]=[C:20]([C:19]3[CH:23]=[CH:24][C:25]([C:27]([F:28])([F:30])[F:29])=[CH:26][C:18]=3[F:17])[O:16][N:15]=2)[CH2:8][CH2:7]1)[CH2:4][CH3:5])[CH3:2]

Participants

3

Reactant 2

HCID 1455802-Fluoro-4-(trifluoromethyl)benzoyl chlorideHCID 178446096HCID 178446096, compound

Product 1

HCID 68805823HCID 68805823, compound

Procedure

The title compound was prepared by a similar procedure to that described in Example 12, starting from 2-((1-ethylpropyl)piperidin-4-yl)-N-hydroxyacetamidine and 2-fluoro-4-trifluoromethylbenzoyl chloride.

Sources & evidence

ORD record
ord-cc2b37eb98434b49b7aeca5dfd190c1d
Source dataset
uspto-grants-2008_02
Patent number
US07332508B2

Reaction notes

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