4-Benzoylbenzoyl chloride → {4-[3-(1-Cyclopropylpiperidin-4-yl)[1,2,4]oxadiazol-5-yl]phenyl}phenylmethanone

HRID 2055698Notes

Reaction equation

HRID 2055698 reaction equation
[CH:1]1([N:4]2[CH2:9][CH2:8][CH:7]([C:10]([NH:12][OH:13])=[NH:11])[CH2:6][CH2:5]2)[CH2:3][CH2:2]1.[C:14]([C:22]1[CH:30]=[CH:29][C:25]([C:26](Cl)=O)=[CH:24][CH:23]=1)(=[O:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH:1]1([N:4]2[CH2:9][CH2:8][CH:7]([C:10]3[N:11]=[C:26]([C:25]4[CH:29]=[CH:30][C:22]([C:14]([C:15]5[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=5)=[O:21])=[CH:23][CH:24]=4)[O:13][N:12]=3)[CH2:6][CH2:5]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 129121414-Benzoylbenzoyl chlorideHCID 178513372HCID 178513372, compound

Product 1

HCID 59657764{4-[3-(1-Cyclopropylpiperidin-4-yl)[1,2,4]oxadiazol-5-yl]phenyl}phenylmethanone

Procedure

The title compound was prepared by a similar procedure to that described in Example 35a, starting from 1-cyclopropyl-N-hydroxypiperidine-4-carboxamidine and 4-benzoylbenzoyl chloride.

Sources & evidence

ORD record
ord-9fb144c1fbbb49bab12f8472fbdcc349
Source dataset
uspto-grants-2008_02
Patent number
US07332508B2

Reaction notes

Loading…