Potassium Carbonate → HCID 73176549, compound

Participants

Reaction Steps

Compound (a5) (3.02 g, 14.80 mmol) was dissolved in dry methanol (10 ml), and the solution was stirred with K2CO3 (1.0 g) at room temp. for 1.5 hrs. After the evaporation of methanol in vacuo, the reaction was quenched with saturated aqueous NaHCO3 solution and the resultant solution was extracted with EtOAc. The organic layer was separated and dried over MgSO4. After filtration, the solvent was evaporated in vacuo. The residue was purified by flash chromatography to give the title compound as an oil in 80% yield.

Provenance & Evidence