HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-ethynylbenzonitrile → 2-[6-(Trimethylsilyl)hex-3-ene-1,5-diyn-1-yl]benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-ethynylbenzonitrile | HCID 11116074 | — |
| Reactant | (4-Chlorobut-3-en-1-yn-1-yl)(trimethyl)silane | HCID 53822143 | — |
| Product | 2-[6-(Trimethylsilyl)hex-3-ene-1,5-diyn-1-yl]benzonitrile | HCID 71374581 | 53% |
Reaction Steps
The Title compound may be produced in two steps using compound a1 Example 1 and compound a3 from Example 3 as starting materials. Firstly, compound a1 and compound a3 were reacted according to Method A set forth in the above-described General Synthesis Procedures I to form 2-(6-trimethylsilyl-3-hexen-1,5-diynyl)benzonitrile, which was subsequently dissolved into into dry methanol with K2CO3 to give a brown oil in 53% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07332623B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-6d359e3b2e90493e976c4074d61abfef |
| Source note | uspto-grants-2008_02 |