HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-t-Butylbenzenesulfonyl chloride → 4-tert-Butyl-N-[4-chloro-2-(4-fluoro-benzoyl)-phenyl]benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-t-Butylbenzenesulfonyl chloride | HCID 139882 | — |
| Reactant | 4-Chloro-2-(4-fluorobenzoyl)aniline | HCID 10955955 | — |
| Product | 4-tert-Butyl-N-[4-chloro-2-(4-fluoro-benzoyl)-phenyl]benzenesulfonamide | HCID 11305378 | — |
Reaction Steps
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 125 mg of (2-Amino-5-chloro-phenyl)-(4-fluoro-phenyl)-methanone and 116 mg of 4-tert-butyl-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 1.21 (s, 9H), 7.09 (t, 2H, J=8.8 Hz), 7.29 (m, 3H), 7.43-7.50 (m, 3H), 7.59 (m, 2H), 7.77 (d, 1H, J=8.8 Hz), 9.72 (s, 1H). MS: m/z 446.0 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335653B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-b58ac950bd2d4b61b0b37cef9394c5e5 |
| Source note | uspto-grants-2008_02 |