HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pivaloyl chloride → HCID 11451228, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | N-(2-cyclopropylethyl)-6-(1-piperazinyl)-3-pyridazinecarboxamide | HCID 66849327 | — |
| Product | HCID 11451228 | HCID 11451228 | — |
Reaction Steps
Following the procedure of Example 3, making variations only as required to use 2,2-dimethylpropionyl chloride in place of isoxazole-5-carbonyl chloride to react with 6-piperazin-1-yl-pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide, the title compound was obtained as a white solid (64% yield). 1H NMR (300 MHz, CDCl3) δ 8.05, 8.01, 6.98, 3.86-3.73, 3.57, 1.57-1.48, 0.79-0.70, 0.52-0.45, 0.16-0.12. MS (ES+) m/z 360.0 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335658B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-ae595fcca3ae404eb796a108fa8cd9a3 |
| Source note | uspto-grants-2008_02 |