HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-fluoro-2-(trifluoromethyl)benzoyl chloride → HCID 11178786, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-fluoro-2-(trifluoromethyl)benzoyl chloride | HCID 2774785 | — |
| Reactant | N-(2-cyclopropylethyl)-6-(1-piperazinyl)-3-pyridazinecarboxamide | HCID 66849327 | — |
| Product | HCID 11178786 | HCID 11178786 | — |
Reaction Steps
Following the procedure of Example 3, making variations only as required to use 3-fluoro-2-trifluoromethylbenzoyl chloride in place of isoxazole-5-carbonyl chloride to react with 6-piperazin-1-yl-pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide, the title compound was obtained as a white powder (31% yield). 1H NMR (300 MHz, CDCl3) δ 8.05, 7.97, 7.65-7.59, 7.29, 7.12, 6.99, 4.05-3.99, 3.89-3.72, 3.54, 3.35, 1.50, 0.76-0.71, 0.48-0.42, 0.10-0.05.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335658B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-c69d38bd14fa42379a0f2485f21686b0 |
| Source note | uspto-grants-2008_02 |