HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Trifluoromethyl)cyclopropane-1-carboxylic acid → HCID 86597223, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Trifluoromethyl)cyclopropane-1-carboxylic acid | HCID 2778306 | — |
| Reactant | 6-Piperazin-1-yl-pyridazin-3-carboxylic acid (3-methylbutyl)amide | HCID 66849322 | — |
| Product | HCID 86597223 | HCID 86597223 | — |
Reaction Steps
Following the procedure of Example 9, making variations only as required to use 1-trifluoromethylcyclopropanecarboxylic acid to react with 6-piperazin-1-yl-pyridazine-3-carboxylic acid (3-methylbutyl)amide, the title compound was obtained as a white powder (72% yield). 1H NMR (300 MHz, CDCl3) δ 8.05, 7.83, 6.98, 3.90-3.80, 3.48, 1.66, 1.48, 1.39-1.35, 1.18-1.14, 0.92. MS (ES+) m/z 414.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335658B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-32e4db63207a467d864d44709944948f |
| Source note | uspto-grants-2008_02 |