N,N-Dimethylethylenediamine → HCID 11279952, compound

Participants

Reaction Conditions

Reaction Steps

104 ml (0.95 mmol; 1.5 equivalents) of N,N-dimethylethylenediamine are added to 195 mg of 2-(2,6-difluorophenyl)-5-methoxy-1,3-benzothiazole-4,7-dione in solution in 20 ml of anhydrous ethanol. The reaction mixture is stirred at 70° C. for 2 hours then the solvent is evaporated off under reduced pressure. The residue is purified on a silica column (eluent: 5% methanol in dichloromethane). 130 mg (yield=57%) of expected compound is obtained in the form of a red powder.

Provenance & Evidence