反应详情

温度

25 °C

5.9 ml (94.2 mmol; 1.5 equivalents) of methyl iodide is added to 10.8 g (62 mmol) of 2,5-difluorobenzenecarbothioamide in solution in 70 ml of acetone. The reaction mixture is maintained under stirring at 25° C. for 24 hours, then the solvent is evaporated off under reduced pressure. Methyl 2,5-difluorobenzene carbimidothioate hydroiodide is obtained (18.4 g; yield=93%), after crystallization from ethyl ether, in the form of beige powder.

1. temperatureThe reaction mixture is maintained
2. customthe solvent is evaporated off under reduced pressure