HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2056629Generated: October 29, 2026
2-Chloroanthraquinone → Anthra(1,9-cd)pyrazol-6(2H)-one
https://huagongshe.com/reaction/2056629
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Chloroanthraquinone | HCID 8553 | — |
| Reactant | Hydrazine | HCID 9321 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Anthra(1,9-cd)pyrazol-6(2H)-one | HCID 8515 | — |
Reaction Steps
Anhydrous hydrazine is added to a solution of 2-chloroanthraquinone (Aldrich) in 10 mL, pyridine, and the mixture heated at 100° C. for 16 hours. The mixture is cooled and the solvent is evaporated in vacuo. The residue is taken in hot 6N HCl, and the solid is collected by filtration. Flash chromatography of the crude material on silica gel affords anthra[1,9cd]pyrazol-6(2H)-one (“Compound 1”) as yellow solids.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07335676B2 |
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| Source dataset | uspto-grants-2008_02 |
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| ORD ID | ord-42f879efd1c34a41a647b862d69e1e83 |
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| Source note | uspto-grants-2008_02 |
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