(1S)-1-(2-([tert-Butyl(dimethyl)silyl]oxy}ethyl)-3,4-dihydro-1H-2-benzopyran-6-carboxamide → (1S)-1-(2-Hydroxyethyl)-3,4-dihydro-1H-2-benzopyran-6-carboxamide

Participants

Reaction Steps

(1S)-1-(2-{[tert-Butyl(dimethyl)silyl]oxy}ethyl)-3,4-dihydro-1H-2-benzopyran-6-carboxamide (1 g, 2.98 mmol) was dissolved in a mixture of acetic acid (10 mL) and water (5 mL), then stirred for 2 h. The solution was evaporated to give a residue that was dried in vacuo at 55° C. to give the title compound as a white solid.

Provenance & Evidence