HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3R)-1-(5-Acenaphthylenyl)-3-methylpiperazine → (1S)-1-{2-[(2R)-4-(5-Acenaphthylenyl)-2-methylpiperazinyl]ethyl}-3,4-dihydro-1H-2-benzopyran-6-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3R)-1-(5-Acenaphthylenyl)-3-methylpiperazine | HCID 69310141 | — |
| Reactant | 2-[(1S)-6-(aminocarbonyl)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl methanesulfonate | HCID 86596012 | — |
| Product | (1S)-1-{2-[(2R)-4-(5-Acenaphthylenyl)-2-methylpiperazinyl]ethyl}-3,4-dihydro-1H-2-benzopyran-6-carboxamide | HCID 69308373 | — |
Reaction Steps
(3R)-1-(5-Acenaphthylenyl)-3-methylpiperazine was condensed with 2-[(1S)-6-(aminocarbonyl)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl methanesulfonate, as described for Example 1b), to yield the title compound. M+H=454.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335660B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-3c8ecc51a118407790f60dc6131a94af |
| Source note | uspto-grants-2008_02 |