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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 205675Generated: October 31, 2026

Dichloromethane → 4-[8-(Cyclopropyl-methyl-amino)-4-oxo-7-trifluoromethyl-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl]-pyridine-2-carbonitrile

https://huagongshe.com/reaction/205675

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant[2-[3-(2-Cyano-pyridin-4-yl)-3-oxo-propionylamino]-5-(cyclopropyl-methyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert.-butyl esterHCID 86586861—
Product4-[8-(Cyclopropyl-methyl-amino)-4-oxo-7-trifluoromethyl-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl]-pyridine-2-carbonitrileHCID 69689220—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-c3c3fb48b32c46709740517980d81a86
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)